Searchable abstracts of presentations at key conferences in endocrinology

ea0029p1097 | Neuroendocrinology | ICEECE2012

Effects of low sodium concentrations on neuronal cell models

Deledda C. , Luciani P. , Benvenuti S. , Giuliani C. , Fibbi B. , Marone I. , Chelli E. , Squecco R. , Francini F. , Forti G. , Peri A.

Hyponatraemia is the most frequent electrolyte disorder encountered in hospitalized patients. Hyponatraemia causes a wide variety of neurological signs and symptoms, depending on the rate and degree of serum sodium drop. The negative effects of low extracellular sodium concentrations ((Na+)) on neuronal cells are known to be due to the entry of fluids into the cells, as a consequence of reduced plasma osmolality. To date, it has not been investigated whether low (Na+) ...